CREATE TABLE IF NOT EXISTS `files` (
  `id` int(11) NOT NULL AUTO_INCREMENT,
  `path` varchar(255) DEFAULT NULL,
  `data` blob,
  PRIMARY KEY (`id`)
) ENGINE=MyISAM DEFAULT CHARSET=cp1251 AUTO_INCREMENT=1 ;

<?php
  error_reporting(E_ALL);
  $file = 'zamena.doc';
  $hand = fopen($file, 'r') or die('Невозможно открыть файл');
  $read = fread($hand, filesize($file)) or die('Невозможно считать файл');
  //echo $read;
  $cnct = mysql_connect('localhost', '---', '---') or die(mysql_error());
  $db = mysql_select_db('zamena', $cnct) or die(mysql_error());
  mysql_query('SET NAMES cp1251');
  $sql = mysql_query("INSERT INTO `files` (`id`, `path`, `data`) VALUES ('null', '$read')") or die(mysql_error());
  if (!$sql) { die('Ошибка запроса!') ; }
  unset ($read);
  fclose($file);
?>              

You have an error in your SQL syntax; check the manual that corresponds to your MySQL server version for the right syntax to use near 'ьФ┴ ' at line 1

fopen($file, 'rb')